A new study has found that some antidepressants are more likely to cause weight gain than others. While these medications help many people manage mental health conditions such as depression and anxiety, weight gain is a side effect that concerns many users.
For some, the fear of gaining weight may prevent them from starting antidepressant treatment, or even cause them to stop using the medications, despite improvements in their mental health. This new research reveals just how much weight gain can occur with commonly prescribed antidepressants.
The study, published in Annals of Internal Medicine, examined the weight changes of over 183,000 patients who started taking antidepressants for the first time. Researchers compared weight data at six, 12, and 24 months.
The results showed that people taking sertraline (brand names Zoloft and Lustral) gained an average of 0.5 pounds after six months. By 24 months, the average weight gain increased to 3.2 pounds.
Other antidepressants, such as escitalopram (Lexapro, Cipralex) and paroxetine (Paxil, Aropax), showed a higher risk of significant weight gain. The study found that escitalopram was associated with a 15% greater risk of gaining at least 5% of their starting weight compared to sertraline. Paroxetine showed a 14% increased risk.
While the study found a link between antidepressant use and weight gain, it did not pinpoint the exact cause. Experts suggest that antidepressants can affect appetite, metabolism, and physical activity levels. Some medications may also increase inflammation, which could make pain or discomfort feel worse, contributing to weight gain.
Unhealthy eating habits, such as consuming processed foods and sugars, combined with reduced physical activity, are other factors that may worsen weight gain. Experts also note that gaining weight can add stress to the joints and muscles, further complicating chronic pain issues.
Interestingly, one antidepressant, bupropion (Wellbutrin, Zyban), showed a slightly different result. The study found that people taking bupropion had a 15% lower risk of gaining significant weight. In fact, bupropion users experienced a slight weight loss at six months, with an average loss of 0.2 pounds before gaining 1.2 pounds by 24 months.
Although weight gain is a known side effect, experts stress that antidepressants can still be essential for managing mental health conditions. The best way to handle any side effects, including weight gain, is to discuss concerns with a healthcare provider. Together, patients and doctors can create a treatment plan that balances mental health improvement with managing potential side effects.
Experts also suggest maintaining a healthy lifestyle through proper nutrition and regular exercise to help prevent weight gain while on medication.
The study serves as a helpful guide for those starting antidepressants, giving them a clearer idea of what to expect regarding weight changes. However, individual experiences can vary, and patients should not avoid medications solely because of the risk of weight gain.
Read more:
- Exploring Alternatives to Antidepressants: A Guide to Mental Health
- Wondering If You Have Bipolar Disorder? Here’s How To Test
- How To Support Someone With Postpartum Anxiety?
