A new study suggests that collagen supplements might help people with ulcerative colitis (UC), a chronic inflammatory bowel disease. However, researchers say more studies are needed before it can be recommended as a treatment. Collagen, a popular supplement often promoted for skin, joint, and weight loss benefits, is now being explored for its potential to ease UC symptoms.
What the Study Found
Researchers in China investigated the effects of fish-derived collagen peptides on ulcerative colitis. They tested the supplement in two ways: in lab dishes (in vitro) and in mice (in vivo). In the lab, collagen reduced inflammation in cells. In mice, collagen peptides lowered inflammation, protected the colon from damage, and improved the balance of gut bacteria. Mice treated with collagen also had less severe UC symptoms compared to those that didn’t receive the supplement.
The study, published in the journal npj Science of Food, suggests collagen peptides could one day become a useful tool for managing UC. However, the lead researcher, Yan Wang from Yanbian University, cautions that these findings are preliminary. “While our research shows promise, we need more studies to understand how collagen works in humans with UC,” Wang said.
Could Collagen Help UC Patients
Although the study results are encouraging, they don’t guarantee that collagen will work the same way in humans. “We need clinical trials to confirm these benefits,” Wang explained. Still, some health experts believe collagen could be a helpful addition to UC management plans for certain individuals.
Jenna Volpe, a registered dietitian and gut health expert, notes that collagen contains glycine, an amino acid that may reduce intestinal inflammation. Collagen also acts as a prebiotic, feeding beneficial gut bacteria. However, Volpe warns that collagen isn’t a cure-all. “It works for some people, but not everyone. I’ve seen mixed results in my clients with UC,” she said. Some people even experience worsened symptoms when taking collagen.
How to Use Collagen Safely
If you’re considering collagen supplements, consult your healthcare provider first. Volpe recommends starting with a small dose—about one teaspoon (five grams)—and gradually increasing to 15–30 grams per day if tolerated. Collagen powder can be added to drinks like coffee or smoothies, or taken as capsules or gummies.
While collagen shows potential, it’s not a replacement for medical treatments or lifestyle changes. “Supplements should complement, not replace, your healthcare team’s recommendations,” Volpe emphasized.
In conclusion, collagen peptides may offer hope for UC patients, but more research is needed to confirm their benefits. For now, consult a professional before adding collagen to your routine.
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